"Tumor-mimicking" multiple sclerosis

Clin Neuropathol. 2003 Sep-Oct;22(5):235-9.


The spectrum of clinical manifestations of multiple sclerosis (MS) may include rare cases where cerebral lesions simulate brain tumors or abscesses on neuroimaging. We report here on a 43-year-old woman with numerous ring-enhancing cystic lesions in the white matter of cerebral hemispheres, brainstem and cerebellum. The radiological picture was overwhelmingly in favor of a metastatic or infectious etiology, but brain biopsy showed subacute demyelination with central necrosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Axons / pathology
  • Biopsy
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / pathology*
  • Cerebral Cortex / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Multiple Sclerosis / diagnosis
  • Multiple Sclerosis / pathology*
  • Myelin Sheath / pathology
  • Tomography, X-Ray Computed*