Bacterial vesicle formation as a mechanism of protein transfer to animals

Cell. 2003 Oct 3;115(1):2-3. doi: 10.1016/s0092-8674(03)00767-0.

Abstract

Gram-negative bacterial vesicle formation is a mechanism for specific secretion and transfer of a protein toxin to animals. This discovery should stimulate work on the mechanism of protein sorting into vesicles and the role of vesicles in bacterial pathogenesis.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bacterial Proteins / metabolism
  • Escherichia coli / metabolism
  • Gram-Negative Bacteria / metabolism*
  • Hemolysin Proteins
  • Membrane Fusion / physiology
  • Protein Transport / physiology
  • Transport Vesicles / metabolism*

Substances

  • Bacterial Proteins
  • Hemolysin Proteins
  • ApxI toxin, Bacteria