Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors

Angew Chem Int Ed Engl. 2003 Oct 6;42(38):4661-4. doi: 10.1002/anie.200351823.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 1-Deoxynojirimycin / analogs & derivatives
  • Drug Evaluation, Preclinical*
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Glucosamine / analogs & derivatives
  • Glucosamine / chemistry
  • Molecular Structure
  • alpha-L-Fucosidase / antagonists & inhibitors*
  • alpha-L-Fucosidase / metabolism

Substances

  • Enzyme Inhibitors
  • fuconojirimycin
  • 1-Deoxynojirimycin
  • alpha-L-Fucosidase
  • Glucosamine