Contact sensitization to benzoyl peroxide

Contact Dermatitis. 1977 Oct;3(5):273-5. doi: 10.1111/j.1600-0536.1977.tb03674.x.


Four formulations of benzoyl peroxide, two 5% and two 10% gels, were assayed for contact sensitizing capability by the human maximization test. Seventy-six per cent became sensitized. Sensitized subjects reacted to all four formulations. Benzoic acid and related compounds failed to elicit an allergic reaction.

MeSH terms

  • Acne Vulgaris / drug therapy
  • Benzoyl Peroxide / adverse effects*
  • Benzoyl Peroxide / therapeutic use
  • Drug Eruptions / etiology*
  • Humans
  • Patch Tests
  • Peroxides / adverse effects*


  • Peroxides
  • Benzoyl Peroxide