[Effect of saponin from Tribulus terrestris on hyperlipidemia]

Zhong Yao Cai. 2003 May;26(5):341-4.
[Article in Chinese]

Abstract

The preventive and therapeutic effects of saponin from Tribulus terrestris L. on diet-induced hyperlipidemia in mice have been studied. It showed that in preventive experiment the saponin could significantly low the levels of serum TC (P < 0.05), LDL-c (P < 0.01) and liver TC (P < 0.05), TG (P < 0.05), and increase the activities of superoxide-dismutase (SOD) in liver. The therapeutic experiment showed that the saponin could significantly reduce the contents of serum TC (P < 0.05) and liver TC (P < 0.01).

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Cholesterol / metabolism
  • Cholesterol, LDL / blood
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / therapeutic use*
  • Hyperlipidemias / drug therapy*
  • Hyperlipidemias / metabolism
  • Hyperlipidemias / prevention & control
  • Hypolipidemic Agents / isolation & purification
  • Hypolipidemic Agents / therapeutic use*
  • Male
  • Mice
  • Phytotherapy*
  • Plants, Medicinal / chemistry
  • Saponins / isolation & purification
  • Saponins / therapeutic use*
  • Superoxide Dismutase / metabolism
  • Tribulus / chemistry*
  • Triglycerides / metabolism

Substances

  • Cholesterol, LDL
  • Drugs, Chinese Herbal
  • Hypolipidemic Agents
  • Saponins
  • Triglycerides
  • Cholesterol
  • Superoxide Dismutase