Abstract
Patients with transitional cell carcinoma of the bladder classically present with irritative voiding symptoms or painless hematuria. Common sites of vascular metastases include the liver (38%), lung (36%), bone (27%), adrenal glands (21%), and intestine (13%). Vascular metastasis to the brain, without a prior history of chemotherapy, is extremely rare. To our knowledge, this is the first report of a patient with bladder transitional cell carcinoma whose original presentation was from a symptomatic, metastatic, cerebellar lesion.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Carcinoma, Transitional Cell / diagnosis
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Carcinoma, Transitional Cell / drug therapy
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Carcinoma, Transitional Cell / secondary*
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Carcinoma, Transitional Cell / surgery
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Cerebellar Ataxia / etiology
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Cerebellar Neoplasms / complications
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Cerebellar Neoplasms / secondary*
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Cerebellar Neoplasms / surgery
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Cisplatin / administration & dosage
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Combined Modality Therapy
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Craniotomy
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Cystectomy
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Doxorubicin / administration & dosage
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Humans
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Male
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Methotrexate / administration & dosage
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Middle Aged
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Radiosurgery
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Urinary Bladder Neoplasms / diagnosis*
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Urinary Bladder Neoplasms / drug therapy
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Urinary Bladder Neoplasms / surgery
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Vinblastine / administration & dosage
Substances
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Vinblastine
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Doxorubicin
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Cisplatin
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Methotrexate