Mononuclear cell magnesium and retention of magnesium after intravenous loading in patients with acute myocardial infarction

Scand J Clin Lab Invest. 1992 Nov;52(7):763-6. doi: 10.3109/00365519209115523.


A magnesium (Mg++) retention test was performed in 19 patients with acute myocardial infarction (AMI) 4-11 days after admission to the coronary care unit. The retention of Mg++ was 45 +/- 23% of the 30 mmol given intravenously. It has been proposed that a retention of more than 20% represents Mg++ deficiency. The mononuclear cell Mg++ concentration before the retention test was on an average slightly higher in the AMI patients than in 25 healthy volunteers (72.5 +/- 24.2 vs. 62.9 +/- 9.2 mumol g-1 protein) indicating no Mg++ depletion in the first group. The reason why patients during the phase of AMI show an increased retention of Mg++ is unknown, but changes in concentrations of several hormones and a reduction in blood glucose could be of importance. Serum concentrations of Mg++ were lower on admission than after 4-11 days. These initial reductions are probably due to increased concentrations of circulating catecholamines during the early hours of AMI.

MeSH terms

  • Adult
  • Female
  • Humans
  • Leukocytes, Mononuclear / metabolism*
  • Magnesium / administration & dosage
  • Magnesium / blood*
  • Magnesium Deficiency / blood
  • Magnesium Deficiency / complications
  • Male
  • Middle Aged
  • Myocardial Infarction / complications
  • Myocardial Infarction / metabolism*
  • Reference Values


  • Magnesium