Gastrointestinal motility disorders and gastrointestinal prokinetic therapy

Vet Clin North Am Small Anim Pract. 2003 Sep;33(5):1007-28, vi. doi: 10.1016/s0195-5616(03)00076-7.

Abstract

Gastrointestinal motility disorders represent a diagnostic and therapeutic challenge. Disorders of gastrointestinal motility may result in accelerated transit, delayed transit, impaired relaxation, or inappropriate relaxation. The delayed transit disorders are the most important motility disorders of companion animals and may involve the esophagus (hypomotility and megaesophagus), stomach (delayed gastric emptying), small intestine (postoperative ileus and intestinal pseudo-obstruction), or colon (constipation and megacolon).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Benzofurans / pharmacology
  • Benzofurans / therapeutic use
  • Cisapride / pharmacology
  • Cisapride / therapeutic use
  • Dog Diseases / diagnosis*
  • Dog Diseases / drug therapy*
  • Dogs
  • Gastrointestinal Agents / pharmacology
  • Gastrointestinal Agents / therapeutic use*
  • Gastrointestinal Motility / drug effects*
  • Indoles / pharmacology
  • Indoles / therapeutic use
  • Intestinal Diseases / diagnosis
  • Intestinal Diseases / drug therapy
  • Intestinal Diseases / veterinary*
  • Motilin / pharmacology
  • Motilin / therapeutic use

Substances

  • Benzofurans
  • Gastrointestinal Agents
  • Indoles
  • prucalopride
  • tegaserod
  • Motilin
  • Cisapride