Does ultrasound core breast biopsy predict histologic finding on excisional biopsy?

Am J Surg. 2003 Oct;186(4):397-9. doi: 10.1016/s0002-9610(03)00281-2.


Background: The purpose of this study was to determine whether ultrasound-guided core breast biopsy accurately predicts the histologic finding of a subsequent excisional procedure.

Methods: Data were collected prospectively from 1997 to 2001 for 832 ultrasound-guided core breast biopsies (USB) that were followed by excisional breast procedure (EP) within 1 year at our institution. The principal histologic finding obtained at USB and EP was identified for each procedure and the degree of agreement was assessed.

Results: The USB histology predicted EP histology in 90% (n = 746) of the procedures. The USB histology was more significant than EP histology in 3% (n = 22) of procedures; USB histology underdetermined EP histology in 7% (n = 64) of procedures. Overall, our results indicate moderate agreement between the principal histology identified at USB relative to that identified at EP.

Conclusions: Ultrasound-guided core breast biopsy is an effective diagnostic method, but sampling limitations do exist.

MeSH terms

  • Biopsy
  • Biopsy, Needle*
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Carcinoma, Ductal, Breast / diagnosis
  • Carcinoma, Ductal, Breast / pathology
  • Carcinoma, Ductal, Breast / surgery
  • Carcinoma, Intraductal, Noninfiltrating / diagnosis
  • Carcinoma, Intraductal, Noninfiltrating / pathology
  • Carcinoma, Intraductal, Noninfiltrating / surgery
  • Carcinoma, Lobular / diagnosis
  • Carcinoma, Lobular / pathology
  • Carcinoma, Lobular / surgery
  • Humans
  • Prospective Studies
  • Ultrasonography, Interventional*