Glial cells and neurotransmission: an inclusive view of synaptic function

Neuron. 2003 Oct 9;40(2):389-400. doi: 10.1016/s0896-6273(03)00607-x.


Glial cells throughout the nervous system are closely associated with synapses. Accompanying these anatomical couplings are intriguing functional interactions, including the capacity of certain glial cells to respond to and modulate neurotransmission. Glial cells can also help establish, maintain, and reconstitute synapses. In this review, we discuss evidence indicating that glial cells make important contributions to synaptic function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Humans
  • Neuroglia / metabolism*
  • Neuroglia / ultrastructure
  • Neurotransmitter Agents / metabolism*
  • Synaptic Transmission / physiology*


  • Neurotransmitter Agents