Usefulness of chronotropic incompetence to dipyridamole in predicting myocardial perfusion defects in heart transplant recipients

Am J Cardiol. 2003 Oct 15;92(8):1001-4. doi: 10.1016/s0002-9149(03)00989-5.

Abstract

The aim of this report was to assess the relation between heart rate response to dipyridamole infusion and perfusion defects at quantitative sestamibi single-photon emission computed tomographic imaging. We demonstrated in 166 heart transplant recipients that chronotropic incompetence to dipyridamole is the only significant and independent predictor of perfusion defects.

MeSH terms

  • Case-Control Studies
  • Coronary Disease / diagnosis*
  • Coronary Disease / diagnostic imaging
  • Dipyridamole*
  • Electrocardiography
  • Female
  • Heart Rate / drug effects*
  • Heart Transplantation / diagnostic imaging*
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • ROC Curve
  • Technetium Tc 99m Sestamibi*
  • Tomography, Emission-Computed, Single-Photon
  • Vasodilator Agents*

Substances

  • Vasodilator Agents
  • Dipyridamole
  • Technetium Tc 99m Sestamibi