Abstract
Both aerosolized and intravenous infusion of iloprost caused a significant decrease in mean pulmonary artery pressure and pulmonary vascular resistance. Although intravenous infusion caused a large decrease in mean systemic arterial pressure, this was only slightly affected by aerosolized iloprost. Aerosolized iloprost caused a significant decrease in the pulmonary-to-systemic vascular resistance ratio; however, intravenous infusion did not cause a prominent decrease in this ratio.
MeSH terms
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Administration, Inhalation
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Adolescent
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Aerosols
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Child
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Child, Preschool
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Heart Defects, Congenital / complications
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Hemodynamics / drug effects
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Humans
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Hypertension, Pulmonary / drug therapy*
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Hypertension, Pulmonary / etiology
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Hypotension / chemically induced
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Iloprost / administration & dosage*
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Iloprost / adverse effects
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Infant
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Infusions, Intravenous
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Pulmonary Wedge Pressure / drug effects
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Vascular Resistance / drug effects
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Vasodilator Agents / administration & dosage*
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Vasodilator Agents / adverse effects
Substances
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Aerosols
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Vasodilator Agents
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Iloprost