Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD

Neurology. 2003 Oct 14;61(7):1000-2. doi: 10.1212/01.wnl.0000083992.28066.7e.


Mutations in DJ-1 are a cause of autosomal recessive parkinsonism. Polymorphism of genes implicated in hereditary forms of parkinsonism may be a predisposing factor in sporadic Parkinson's disease (PD). The authors analyzed whether a polymorphism (g.168_185del) within exon 1 of DJ-1 contributes to the risk of sporadic PD in a Finnish case-control series. This gene does not play a major role in the genetic predisposition to PD in this population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Alleles
  • DNA Mutational Analysis
  • Female
  • Finland / epidemiology
  • Genetic Predisposition to Disease
  • Genetic Testing
  • Genotype
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Male
  • Middle Aged
  • Oncogene Proteins / genetics*
  • Parkinson Disease / epidemiology
  • Parkinson Disease / genetics*
  • Polymorphism, Genetic / genetics*
  • Protein Deglycase DJ-1
  • Risk Assessment


  • Intracellular Signaling Peptides and Proteins
  • Oncogene Proteins
  • PARK7 protein, human
  • Protein Deglycase DJ-1