Genetic interactions between FLM and other flowering-time genes in Arabidopsis thaliana

Plant Mol Biol. 2003 Jul;52(5):915-22. doi: 10.1023/a:1025426920923.


FLOWERING LOCUS M (FLM) is a MADS-domain gene that acts as an inhibitor of flowering in Arabidopsis. Here we describe the genetic interaction of FLM with genes in the photoperiod and autonomous flowering pathways. Although the sequence of FLM is most similar to that of FLC, FLM and FLC interact with different flowering pathways. It has been previously shown that flc lesions suppress the late-flowering phenotype of FRI-containing lines and autonomous-pathway mutants. However, flm lesions suppress the late-flowering phenotype of photoperiod-pathway mutants but not that of FRI-containing lines or autonomous-pathway mutants. Another MADS-domain flowering repressor with a mutant phenotype similar to FLM is SVP. The late-flowering phenotype of FLM over-expression is suppressed by the svp mutation, and an svp flm double mutant behaves like the single mutants. Thus FLM and SVP are in the same flowering pathway which interacts with the photoperiod pathway.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / growth & development
  • Arabidopsis Proteins / genetics*
  • Flowers / genetics*
  • Flowers / growth & development
  • Gene Expression Regulation, Developmental
  • Gene Expression Regulation, Plant
  • MADS Domain Proteins / genetics
  • Models, Genetic
  • Mutation
  • Phenotype
  • Photoperiod
  • RNA, Plant / genetics
  • RNA, Plant / metabolism
  • Signal Transduction / genetics
  • Suppression, Genetic
  • Time Factors
  • Transcription Factors / genetics


  • Arabidopsis Proteins
  • FLF protein, Arabidopsis
  • MADS Domain Proteins
  • RNA, Plant
  • SVP protein, Arabidopsis
  • Transcription Factors