Eugenio Espejo (1747-1795). Mestizo. Was born in the Royal Audience of Quito. Today, the Republic of Ecuador. The 18th century was isf illustration and enlightment for the Quiteños. Espejo's extraordinary erudition is explained by the full access he had to yhe libraries created in Quito by the Jesuits. The best in the continent at that time. His work, Reflections on Smallpox, makes or Espejo outstanding in his field. Pioneer in bacteriology and of the biopathological observations in America. The first newspaper in Quito, Primicies of the culture of Quito, was his own work. Furthermore, Espejo is considered the precursor of the independence of Hispanoamerica.