Abstract
Regulation of transcription of the tryptophanase operon requires that translation of its leader peptide coding region, tnaC, be coupled with its transcription. We show in vitro that a transcription pause site exists at the end of the tnaC coding region and that translation of tnaC releases the paused transcription complex, coupling transcription with translation.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amino Acid Sequence
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Bacterial Proteins / genetics
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Base Sequence
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Escherichia coli Proteins / genetics
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Molecular Sequence Data
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Nucleic Acid Conformation
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Operon*
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Protein Biosynthesis*
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Transcription, Genetic*
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Tryptophanase / genetics*
Substances
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Bacterial Proteins
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Escherichia coli Proteins
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tnaC protein, E coli
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Tryptophanase