Benzotriazole: an ideal synthetic auxiliary

Chemistry. 2003 Oct 6;9(19):4586-93. doi: 10.1002/chem.200304990.

Abstract

Benzotriazole is a synthetic auxiliary that offers many advantages. It is inexpensive, odorless, and stable. A benzotriazole group is easily introduced, activates molecules towards numerous transformations, and can be removed easily at the end of the reaction sequence. This Concept provides some recent examples of the synthetic application of benzotriazole methodology and is intended to draw attention to the versatile applications of benzotriazole in organic chemistry.