[Study on prevention and treatment of radiotherapy caused post-visual pathway injury in nasopharyngeal carcinoma patients by traditional Chinese medicine]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2003 Sep;23(9):661-3.
[Article in Chinese]

Abstract

Objective: To study the effect of TCM in preventing and treating post-visual pathway injury caused by radiotherapy (RT) for nasopharyngeal carcinoma (NPC).

Methods: Thirty-five patients of NPC were randomly divided into the RT group (n = 17) and the RT + TCM group (n = 18), they were all received RT, but the latter was treated additionally with Jingming recipe, a Chinese recipe. The latent period and amplitude of evoked potential (EP) were measured before and after ending of RT, using multi-focusing visual evoked potential inspector.

Results: The latent time of EP, both upper and lower visual field, was prolonged significantly after RT in the RT group (P < 0.05), but not in the RT + TCM group (P > 0.05); the amplitude of EP of upper visual field lowered significantly (P < 0.05) in the RT group but insignificantly in the RT + TCM group (P > 0.05); as for the EP amplitude of lower visual field, it was unaltered in RT group after RT (P > 0.05), but increased in the RT + TCM group (P < 0.05).

Conclusion: The Chinese medicine Jingming recipe was effective in preventing and treating RT induced post-visual pathway injury.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Drugs, Chinese Herbal / therapeutic use*
  • Evoked Potentials, Visual
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nasopharyngeal Neoplasms / drug therapy
  • Nasopharyngeal Neoplasms / radiotherapy*
  • Phytotherapy*
  • Radiation Injuries / prevention & control*
  • Visual Pathways / injuries*

Substances

  • Drugs, Chinese Herbal