Factors associated with atypical speech representation in children with intractable epilepsy

Neuropsychologia. 2003;41(14):1967-74. doi: 10.1016/s0028-3932(02)00323-8.


The purpose of this study was to investigate the relationship between hemispheric speech dominance and several demographic and seizure variables in a large sample of children (N=75) who underwent the intracarotid amobarbital procedure (IAP) prior to surgery. The findings were similar to results previously reported in adults and children, suggesting that variables, such as age at seizure onset, laterality of seizure focus, location of seizure focus and handedness are related to the presentation of atypical speech representation in children with epilepsy. The impact of multiple variables in determining the risk for atypical speech dominance was also assessed. The results demonstrated an increased probability of atypical speech representation in children with a greater number of risk variables, suggesting the need for further investigations in this area.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Age of Onset
  • Child
  • Epilepsy / complications*
  • Epilepsy / epidemiology
  • Female
  • Functional Laterality*
  • Humans
  • Language Disorders / epidemiology
  • Language Disorders / etiology*
  • Language Tests
  • Male
  • Neuropsychological Tests
  • Seizures / physiopathology
  • Speech