Management of hereditary angioedema: a Canadian approach

Transfus Apher Sci. 2003 Dec;29(3):205-14. doi: 10.1016/j.transci.2003.08.009.


C1 esterase inhibitor (C1-INH) deficiency is a rare disorder that lacks consensus for diagnosis therapy and management. Recognizing that Canada is behind the European approach to this disorder, we have formed the Canadian Hereditary Angioedema Society (CHAES)/Société d'angioédème héréditaire du Canada (SAHC) to foster knowledge of this disorder in Canada and to advance care of patients with this disorder in Canada. We here present a review of treatment of this disorder in Canada including prevention of angioedema events and use of replacement therapy and present an algorithm for diagnosis therapy and management of C1-INH deficiency in Canada for discussion at our International Conference on Hereditary Angioedema to be held in Toronto, Canada, October 24th to 26th, 2003.

MeSH terms

  • Algorithms
  • Angioedema / diagnosis
  • Angioedema / therapy*
  • Canada
  • Complement C1 Inactivator Proteins / deficiency*
  • Congresses as Topic
  • Guidelines as Topic
  • Humans
  • Societies


  • Complement C1 Inactivator Proteins