Cancer: a twist in a hedgehog's tale

Nature. 2003 Oct 23;425(6960):780-2. doi: 10.1038/425780a.
No abstract available

Publication types

  • News
  • Comment

MeSH terms

  • Animals
  • Cell Division / drug effects
  • Gastrointestinal Neoplasms / drug therapy
  • Gastrointestinal Neoplasms / genetics*
  • Gastrointestinal Neoplasms / metabolism*
  • Gastrointestinal Neoplasms / pathology
  • Gene Expression Regulation, Neoplastic*
  • Hedgehog Proteins
  • Humans
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism
  • Patched Receptors
  • Receptors, Cell Surface
  • Receptors, G-Protein-Coupled / antagonists & inhibitors
  • Receptors, G-Protein-Coupled / genetics
  • Receptors, G-Protein-Coupled / metabolism
  • Signal Transduction* / drug effects
  • Smoothened Receptor
  • Trans-Activators / antagonists & inhibitors
  • Trans-Activators / genetics*
  • Trans-Activators / metabolism*
  • Veratrum Alkaloids / pharmacology
  • Veratrum Alkaloids / therapeutic use

Substances

  • Hedgehog Proteins
  • Membrane Proteins
  • Patched Receptors
  • Receptors, Cell Surface
  • Receptors, G-Protein-Coupled
  • SMO protein, human
  • Smoothened Receptor
  • Trans-Activators
  • Veratrum Alkaloids
  • cyclopamine