Report of accidental CS ingestion among seven patients in central Israel and review of the current literature

Arch Toxicol. 2003 Oct;77(10):601-4. doi: 10.1007/s00204-003-0479-2. Epub 2003 Jul 30.


A report of seven people who accidentally drank a juice contaminated with CS (o-chlorobenzylidene malononitrile) is given. Due to its mucosal irritating properties, CS (also known as "tear gas") is commonly used by policemen and soldiers in riot control. However, only a few reports of its ingestion by humans exist. Ingestion of CS may cause immediate irritation of the oral mucosa and gastrointestinal symptoms later on. Damage of internal organs, which has been shown in animals but only rarely in humans, is probably related to the dose ingested. The extensive use of CS gas merits recognition of the signs and symptoms of its exposure in order to reduce anxiety in both patients and medical staff and to facilitate fast and efficient management.

Publication types

  • Review

MeSH terms

  • Adult
  • Beverages / poisoning
  • Female
  • Humans
  • Male
  • Riot Control Agents, Chemical / metabolism
  • Riot Control Agents, Chemical / poisoning*
  • o-Chlorobenzylidenemalonitrile / metabolism
  • o-Chlorobenzylidenemalonitrile / poisoning*


  • Riot Control Agents, Chemical
  • o-Chlorobenzylidenemalonitrile