Abstract
A convenient strategy for the synthesis of the analogue of cyclic oligodeoxyribonucleotides is presented. The cyclization of the oligonucleotide was accomplished through intramolecular oxime bond formation between a 5'-oxyamine moiety and a 3'-aldehydic group.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehydes / chemistry
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Cyclization
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DNA, Circular / chemical synthesis*
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Models, Chemical
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Oligodeoxyribonucleotides / chemical synthesis*
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Oximes / chemical synthesis*
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Sequence Analysis
Substances
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Aldehydes
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DNA, Circular
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Oligodeoxyribonucleotides
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Oximes