Dermal melanocytic proliferation with features of a plaque-type blue nevus and neurocristic hamartoma

J Am Acad Dermatol. 2003 Nov;49(5):924-9. doi: 10.1016/s0190-9622(03)00477-8.


Blue nevi (BN) and neurocristic hamartomas (NCH) are pigmented lesions that originate from the aberrant development of cells derived from the neural crest. BN are composed of dermal melanocytes, whereas NCH have a broader histology and show Schwann cell differentiation as well. In addition, BN and NCH might differ in their potential to develop into a malignancy. We describe a patient with a lesion showing features of both a plaque-type BN and NCH.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cell Division
  • Female
  • Hamartoma / pathology*
  • Humans
  • Melanocytes / pathology*
  • Nevus, Blue / pathology*
  • Skin Neoplasms / pathology*