Organocatalytic asymmetric Michael reaction of cyclic 1,3-dicarbonyl compounds and alpha,beta-unsaturated ketones--a highly atom-economic catalytic one-step formation of optically active warfarin anticoagulant

Angew Chem Int Ed Engl. 2003 Oct 20;42(40):4955-7. doi: 10.1002/anie.200352136.

Authors

Nis Halland¹, Tore Hansen, Karl Anker Jørgensen

Affiliation

¹ The Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark.

PMID: 14579449
DOI: 10.1002/anie.200352136

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anticoagulants / chemical synthesis*
Anticoagulants / chemistry
Catalysis
Cyclization
Ketones / chemistry*
Models, Molecular
Molecular Conformation
Molecular Structure
Stereoisomerism
Warfarin / chemical synthesis*
Warfarin / chemistry

Substances

Anticoagulants
Ketones
Warfarin