Botulinum toxin in the management of bowel and bladder function in spinal cord injury and other neurologic disorders

Phys Med Rehabil Clin N Am. 2003 Nov;14(4):793-804, vi. doi: 10.1016/s1047-9651(03)00065-2.

Abstract

Botulinum toxin inhibits release of acetylcholine and other neurotransmitters. It has been used successfully to treat pain and abnormal skeletal and smooth muscle activity in patients. This article discusses its use in patients with bladder and bowel disorders.

Publication types

  • Review

MeSH terms

  • Anti-Dyskinesia Agents / therapeutic use*
  • Anus Diseases / drug therapy
  • Autonomic Dysreflexia / drug therapy
  • Autonomic Dysreflexia / etiology
  • Botulinum Toxins / therapeutic use*
  • Constipation / drug therapy
  • Humans
  • Randomized Controlled Trials as Topic
  • Spinal Cord Injuries / complications*
  • Urinary Bladder, Neurogenic / drug therapy*
  • Urinary Bladder, Neurogenic / etiology

Substances

  • Anti-Dyskinesia Agents
  • Botulinum Toxins