Targeting the PI3K-Akt pathway in human cancer: rationale and promise

Cancer Cell. 2003 Oct;4(4):257-62. doi: 10.1016/s1535-6108(03)00248-4.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Cycle
  • Cell Division
  • Cell Survival
  • Humans
  • Mice
  • Models, Animal
  • Neoplasms / drug therapy
  • Neoplasms, Experimental / physiopathology
  • Phosphatidylinositol 3-Kinases / metabolism*
  • Phosphorylation
  • Protein Interaction Mapping
  • Protein-Serine-Threonine Kinases*
  • Proto-Oncogene Proteins / metabolism*
  • Proto-Oncogene Proteins c-akt
  • Signal Transduction

Substances

  • Proto-Oncogene Proteins
  • Phosphatidylinositol 3-Kinases
  • AKT1 protein, human
  • Protein-Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-akt