The role of immunosuppression in recurrence of hepatitis C

Liver Transpl. 2003 Nov;9(11):S63-6. doi: 10.1053/jlts.2003.50264.

Abstract

1. Recurrent hepatitis C is an increasing problem posttransplantation. 2. It is difficult to determine histologically if alloimmunity, i.e., rejection, is also plays a role in posttransplantation hepatitis C. 3. Change in the degree of immunosuppression, rather than the absolute amount of immunosuppression, is bad for HCV-infected recipients. 4. Corticosteroid boluses are bad for HCV-infected recipients.

Publication types

  • Review

MeSH terms

  • Graft Rejection / drug therapy
  • Graft Rejection / immunology*
  • Graft Rejection / pathology
  • Hepatitis C / immunology*
  • Hepatitis C / surgery
  • Humans
  • Immunosuppression*
  • Immunosuppressive Agents / therapeutic use
  • Liver Transplantation / immunology
  • Mycophenolic Acid / analogs & derivatives*
  • Mycophenolic Acid / therapeutic use
  • RNA, Viral / blood
  • Recurrence

Substances

  • Immunosuppressive Agents
  • RNA, Viral
  • Mycophenolic Acid