Copper(II)-catalysed aerobic oxidation of primary alcohols to aldehydes

Patrick Gamez; Isabel W C E Arends; Jan Reedijk; Roger A Sheldon

doi:10.1039/b308668b

Copper(II)-catalysed aerobic oxidation of primary alcohols to aldehydes

Chem Commun (Camb). 2003 Oct 7:(19):2414-5. doi: 10.1039/b308668b.

Authors

Patrick Gamez¹, Isabel W C E Arends, Jan Reedijk, Roger A Sheldon

Affiliation

¹ Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands.

PMID: 14587708
DOI: 10.1039/b308668b

Abstract

[CuBr2(2,2'-bipyridine)] catalyses the selective and very mild aerobic oxidation of primary alcohols to aldehydes in acetonitrile:water (2:1) in the presence of 2,2,6,6-tetramethylpiperidinyl-1-oxy (TEMPO) and a base as cocatalysts.