Anguilla anguilla L. plasma cortisol, lactate and glucose responses to abietic acid, dehydroabietic acid and retene

Environ Int. 2004 Jan;29(7):995-1000. doi: 10.1016/S0160-4120(03)00093-X.

Abstract

Anguilla anguilla L. were exposed to 0, 0.1, 0.3, 0.9 and 2.7 microM abietic (AA), dehydroabietic (DHAA) acids and retene (Re) during 8, 16, 24 and 72 h. The eels plasma cortisol, glucose and lactate were measured. A significant decrease in plasma cortisol was observed at 72 h exposure to 0.9 and 2.7 microM Re. DHAA (0.1 microM) significantly decreased plasma cortisol in eels after 8 and 24 h exposure. However, a significant plasma cortisol increase was found after 16 h, 2.7 microM AA exposure and after 24 h exposure to 0.1 microM and 2.7 microM AA. Furthermore, 72 h exposure to 0.9 microM AA also induced a plasma cortisol increase. A general rise in plasma glucose was detected after all exposure periods to Re. The plasma lactate also increased after 72 h exposure to 2.7 microM AA and after 8 h exposure to 0.1 microM DHAA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abietanes / toxicity*
  • Anguilla / physiology*
  • Animals
  • Blood Glucose*
  • Free Radical Scavengers / toxicity*
  • Hydrocortisone / blood*
  • Lactic Acid / blood*
  • Phenanthrenes / toxicity*

Substances

  • Abietanes
  • Blood Glucose
  • Free Radical Scavengers
  • Phenanthrenes
  • dehydroabietic acid
  • retene
  • Lactic Acid
  • abietic acid
  • Hydrocortisone