Standards of measurements in myasthenia gravis

Ann N Y Acad Sci. 2003 Sep;998:445-52. doi: 10.1196/annals.1254.058.


Valid and reliable measurements of muscle impairment are needed to assess therapeutic efficacy in patients with generalized myasthenia gravis. Several muscle scoring systems have been proposed for assessing muscle strength in such patients. The aim of the present study is to assess the validity and interobserver agreement of these muscle scores.

Publication types

  • Comparative Study

MeSH terms

  • Activities of Daily Living
  • Diagnosis, Differential
  • Disability Evaluation
  • Humans
  • Muscle Weakness / physiopathology*
  • Muscles / physiopathology
  • Myasthenia Gravis / diagnosis*
  • Myasthenia Gravis / epidemiology
  • Myasthenia Gravis / physiopathology*
  • Myasthenia Gravis / therapy
  • Observer Variation
  • Reference Standards
  • Reproducibility of Results
  • Research Design*
  • Severity of Illness Index*
  • Statistics as Topic