Mycobacterium avium rough-to-smooth colony conversion resulting from growth in Tween 80 without presence of type-specific glycopeptidolipid antigens

FEMS Microbiol Lett. 1992 Nov 1;77(1-3):209-16. doi: 10.1016/0378-1097(92)90158-k.


Growth of a Mycobacterium avium complex serotype 20 rough-colony variant in 1.0% Tween 80 resulted in a smooth-colony morphological conversion that was reversible upon removal of Tween and was not associated with the presence of serotype-specific glycopeptidolipid antigens. Electron microscopic examination suggested the role of an outer layer in the Tween-related morphological modification.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antigens, Bacterial
  • Culture Media
  • Glycolipids / immunology
  • Glycopeptides / immunology
  • Microscopy, Electron
  • Mycobacterium avium / classification
  • Mycobacterium avium / immunology
  • Mycobacterium avium / ultrastructure*
  • Polysorbates
  • Serotyping


  • Antigens, Bacterial
  • Culture Media
  • Glycolipids
  • Glycopeptides
  • Polysorbates