Mechanism of migration from agglomerated cork stoppers. Part 2: Safety assessment criteria of agglomerated cork stoppers for champagne wine cork producers, for users and for control laboratories

Food Addit Contam. 2003 Oct;20(10):960-71. doi: 10.1080/02652030310001597583.


Producers of cork for champagne and wine have to be certain the corks meet the requirements of the European Union Framework Directive, and comply with the evaluations of chemicals carried out in the European Union. To identify chemicals in cork with the potential to migrate, the different synthetic products on the market were classified based on their technical role and of the chemistry involved. The potential migrants in each class (adhesive for cork bodies, adhesive for cork disks, lubricants and surface treatments) were analysed spectroscopically and chromatographically. A general approach was proposed for the evaluation of each commercial chemical: the detailed composition was supplied and verified mainly by infrared spectroscopy, proton nuclear magnetic resonance spectroscopy ((1)H-NMR) and GC-MS. A procedure to determine primary aromatic amines, specifically for cork migrates, based on GC-MS was developed. These techniques focussed on migrants below 1000 g mol(-1), as higher molecular weight chemicals are not likely to pose a problem for public health. The products were also tested after polymerization. The analytical scheme included an analytical check of synthetic product formulation and identification of potential migrants, solvent extraction and analysis of cork extracts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adhesives / chemistry
  • Consumer Product Safety* / legislation & jurisprudence
  • Diffusion
  • European Union
  • Food Contamination / prevention & control*
  • Food Packaging / legislation & jurisprudence
  • Food Packaging / standards*
  • Gas Chromatography-Mass Spectrometry / methods
  • Humans
  • Materials Testing / methods
  • Paraffin / chemistry
  • Silicones / chemistry
  • Trees
  • Wine*


  • Adhesives
  • Silicones
  • Paraffin