Liliequist membrane: three-dimensional constructive interference in steady state MR imaging

Radiology. 2003 Nov;229(2):360-5; discussion 365. doi: 10.1148/radiol.2292021507.


Purpose: To evaluate the Liliequist membrane in healthy volunteers by using three-dimensional (3D) Fourier transformation constructive interference in steady state (CISS) magnetic resonance (MR) imaging.

Materials and methods: In 31 volunteers, the authors performed 3D CISS MR imaging. They divided the membrane into three segments: the sellar, diencephalic, and mesencephalic segments. MR images were evaluated to identify the segments, superior and inferior attachments, lateral border, and thickness of the Liliequist membrane.

Results: Three-dimensional CISS MR imaging depicted the sellar, diencephalic, and mesencephalic segments of the Liliequist membrane in the sagittal plane in 25 (81%), 16 (52%), and five (16%) of the 31 subjects, respectively. Transverse MR imaging depicted these segments in 24 (77%), 10 (32%), and two (6%) subjects, respectively, and coronal MR imaging depicted them in 24 (77%), 12 (39%), and two (6%) subjects, respectively. Clear attachment of the membrane to the dorsum sellae was observed in 22 (88%) of 25 subjects in whom the sellar segment was identified. Clear attachment to the mamillary body was identified in eight (50%) of 16 subjects in whom the diencephalic segment was identified. The Liliequist membrane was attached to the oculomotor nerve on seven (14%) of 50 sides of the lateral border and to the arachnoid membrane around the oculomotor nerve on 28 (56%) sides. In the sagittal plane, the thickness of the membrane was less than one-half the thickness of the third ventricle floor in 22 (88%) of 25 subjects.

Conclusion: The Liliequist membrane can be visualized by using 3D CISS MR sequences.

MeSH terms

  • Adult
  • Arachnoid / anatomy & histology*
  • Brain / anatomy & histology*
  • Diencephalon / anatomy & histology
  • Female
  • Humans
  • Imaging, Three-Dimensional*
  • Magnetic Resonance Imaging*
  • Male
  • Mesencephalon / anatomy & histology
  • Middle Aged
  • Oculomotor Nerve / anatomy & histology
  • Reference Values