Review of operative indication and prognosis in gastric cancer with hepatic cirrhosis

Hepatogastroenterology. 1992 Oct;39(5):433-6.


Prognosis following surgery for gastric cancer has markedly improved as a result of early diagnosis, advances in operative techniques, and perioperative management. However, gastrointestinal surgery in patients with hepatic cirrhosis has continued to be associated with a high operative morbidity and mortality. On the basis of a detailed classification of the preoperative hepatic conditions into three risk groups, we have established a preoperative means of assessing surgical indication. Depending on the preoperative assessment, 40 gastric cancer patients with hepatic cirrhosis underwent surgical exploration. Thirty-seven patients (92.5%) received gastric resection, while 3 patients (7.5%) were non-resectable. Postoperative complications occurred in only 8 patients (20%), and no anastomotic leakage occurred; the overall operative mortality was zero. The five-year-survival rate following a curative resection, as calculated by Kaplan-Meier statistical analysis, was 51.4% (n = 30).

MeSH terms

  • Female
  • Gastrectomy
  • Humans
  • Liver Cirrhosis / complications*
  • Liver Cirrhosis / surgery
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology
  • Postoperative Complications / mortality
  • Prognosis
  • Risk
  • Stomach Neoplasms / complications
  • Stomach Neoplasms / surgery*
  • Surgical Procedures, Operative / methods
  • Survival Rate