Revascularization and ventricular restoration in patients with ischemic heart failure: the STICH trial

Curr Opin Cardiol. 2003 Nov;18(6):454-7. doi: 10.1097/00001573-200311000-00006.


Purpose of review: As techniques for the management of patients with ischemic heart failure have evolved, controversy has arisen with respect to the roles of revascularization and ventricular restoration procedures. This review addresses current thinking on the management of these patients and describes a prospective randomized trial that will have an impact on future treatment selection.

Recent findings: Although the basis for improved survival with coronary artery bypass grafting lies in the viability of ischemic myocardium, nuclear medicine studies and stress echocardiography have failed to adequately select for tissues that are capable of recovery. Recent studies have suggested an additional benefit to combining ventricular restoration with bypass surgery. However, the role for these techniques has not been definitively established.

Summary: The currently enrolling Surgical Treatment for Ischemic Heart Failure (STICH) trial promises to address these issues and thereby improve the management of patients with this disease.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Review

MeSH terms

  • Coronary Artery Bypass*
  • Heart Failure / physiopathology*
  • Heart Failure / surgery*
  • Heart Ventricles / physiopathology
  • Heart Ventricles / surgery
  • Humans
  • Myocardial Ischemia / physiopathology*
  • Myocardial Ischemia / surgery*
  • United States / epidemiology
  • Ventricular Dysfunction, Left / physiopathology
  • Ventricular Dysfunction, Left / surgery
  • Ventricular Function / physiology*