In the middle of the XV. century, the Ottoman Empire was an powerful government all the Turc and Islam geography. Many wises and students who belong to the Turc's world came here. Isfahanli Giyas b. Muhammed is one of these scientists. He finished education in his country and then he came. Amasya and he took lessons from Sabuncuoğlu about medical information and he returned back to his country. He wrote a medical book which named Mir'atü's-Sihha and he dedicated to Ottoman's sultan II. Bayezid. In this book's within, there was a poem who exalted the II. Bayezid.