Bacteriocidal activity of garlic powder against Bacillus anthracis

J Nutr Sci Vitaminol (Tokyo). 2003 Aug;49(4):297-9. doi: 10.3177/jnsv.49.297.

Abstract

The antibacterial activity of garlic powder was examined against Bacillus anthracis using agar plate cultivation and test tube methods. On the agar plate test, 1-5% garlic powder inhibited the growth of B. anthracis and Escherichia coli O157 used as references. A 1% water solution of garlic powder in the test tube method killed B. anthracis at 10(7) cfu/mL within 3 h of treatment at room temperature. A number of intestinal bacteria in a BALB/c mouse decreased after the oral administration of 1 mL of 1%, garlic powder solution once a day for 3 d. These results suggest that the oral administration of garlic powder is effective against pathogenic bacteria invasion into the intestine as an infection.

MeSH terms

  • Administration, Oral
  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Bacillus anthracis / drug effects*
  • Bacillus anthracis / growth & development
  • Colony Count, Microbial
  • Garlic* / chemistry
  • Kinetics
  • Mice
  • Mice, Inbred BALB C
  • Microbial Sensitivity Tests
  • Plant Extracts / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Plant Extracts