2-Hydroxyflavanones from Leptospermum polygalifolium subsp. polygalifolium Equilibrating sets of hemiacetal isomers

Kamarul'Ain Mustafa; Nigel B Perry; Rex T Weavers

doi:10.1016/j.phytochem.2003.09.006

2-Hydroxyflavanones from Leptospermum polygalifolium subsp. polygalifolium Equilibrating sets of hemiacetal isomers

Phytochemistry. 2003 Dec;64(7):1285-93. doi: 10.1016/j.phytochem.2003.09.006.

Authors

Kamarul'Ain Mustafa¹, Nigel B Perry, Rex T Weavers

Affiliation

¹ Department of Chemistry, University of Otago, PO Box 56, Dunedin, New Zealand.

PMID: 14599527
DOI: 10.1016/j.phytochem.2003.09.006

Abstract

2,5-Dihydroxy-6-methyl-7-methoxyflavanone and its isomer 2,5-dihydroxy-8-methyl-7-methoxyflavanone have been identified as the principal components in the ethanol extract of L. polygalifolium subsp. polygalifolium. The former compound has been separated from the latter for the first time by crystallisation. Other flavonoids identified include an equilibrating mixture of novel 2,3,5-trihydroxyflavanones; the first discovery of this type of compound from a natural source. This study has also confirmed the presence of the triketones, flavesone and leptospermone, along with the closely related isoleptospermone as anti-microbial components.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetals / chemistry*
Chemical Fractionation / methods
Flavanones / chemistry*
Flavanones / isolation & purification*
Isomerism
Kinetics
Leptospermum / chemistry*
Models, Molecular
Molecular Conformation
Nuclear Magnetic Resonance, Biomolecular / methods
Plant Extracts / chemistry

Substances

Acetals
Flavanones
Plant Extracts