ent-Labdane diterpenes from the aquatic plant Potamogeton pectinatus

Phytochemistry. 2003 Dec;64(7):1309-17. doi: 10.1016/j.phytochem.2003.08.014.

Abstract

Four new ent-labdane diterpenes were isolated from the freshwater aquatic plant Potamogeton pectinatus, together with two known furano-ent-labdanes. The new compounds were assigned the structures methyl-15,16-epoxy-12(R)-acetoxy- 8(17), 13(16),14-ent-labdatrien-19-oate,15,16-epoxy-12(R)-acetoxy-8(17), 13(16),14-ent-labdatrien-19-oic acid, 8(17),13-ent-labdadien-15 --> 16-lactone-19-oic acid and 16-hydroxy-8(17),13-ent-labdadien-15,16-olid-19-oic acid by spectroscopic means. Some of these labdanes showed a strong algicidal activity against Raphidocelis subcapitata.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chlorophyta / drug effects
  • Chlorophyta / growth & development
  • Chromatography, Liquid / methods
  • Diterpenes / chemistry*
  • Diterpenes / isolation & purification*
  • Diterpenes / pharmacology
  • Inhibitory Concentration 50
  • Mass Spectrometry / methods
  • Nuclear Magnetic Resonance, Biomolecular / methods
  • Potamogetonaceae / chemistry*
  • Spectrophotometry, Ultraviolet / methods

Substances

  • Diterpenes
  • labdane