Management of advanced pelvic cancer by exenteration

Eur J Surg Oncol. 2003 Nov;29(9):743-6. doi: 10.1016/j.ejso.2003.08.008.

Abstract

Aim: To describe our results in managing locally advanced primary or recurrent pelvic malignancies.

Method: Investigations included: clinical, laboratory, endoscopic (rectoscopy and colonoscopy) examinations, ultrasound scan, and CT scan or MRI of the abdomen and pelvis, to determine the extent of the pelvic malignancy. A careful explorative laparatomy of abdomen and pelvis was performed, followed by anterior, posterior or total pelvic exenteration.

Results: In the period June 1995-Jan 2002, 7 anterior, 2 posterior and 51 total pelvic exenterations were performed in 60 patients, distributed as follows: 28 for rectal cancer (12 primary, 16 recurrent), 20 for cervical cancer (9 primary, 11 recurrent) and 12 for other pelvic malignancies. The median survival time and overall 5-year survival rates were as follows: primary rectal cancer--50 months and 32%; recurrent rectal cancer--31 months and 17%; primary cervical cancer--46.4 months and 41% and recurrent cervical cancer--23.4 months and 16%. During the same period, 559 of our patients were treated for primary or recurrent rectal cancer by different types of straightforward resection.

Conclusion: Pelvic exenteration is justifiable in cases of locally advanced primary and recurrent malignancies of rectum, cervical cancer and possibly in cases of other pelvic malignancies.

Publication types

  • Evaluation Study

MeSH terms

  • Colorectal Neoplasms / mortality
  • Colorectal Neoplasms / surgery
  • Female
  • Humans
  • Laparoscopy
  • Magnetic Resonance Imaging
  • Male
  • Neoplasm Metastasis
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Recurrence, Local / mortality*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery*
  • Outcome Assessment, Health Care
  • Palliative Care
  • Pelvic Exenteration*
  • Pelvic Neoplasms / diagnostic imaging
  • Pelvic Neoplasms / mortality*
  • Pelvic Neoplasms / pathology
  • Pelvic Neoplasms / surgery*
  • Survival Analysis
  • Tomography, X-Ray Computed
  • Ultrasonography
  • Yugoslavia