Abstract
Preliminary microbial metabolism studies of bisphenol A (BPA) (1) on twenty six microorganisms have shown that Aspergillus fumigatus is capable of metabolizing BPA. Scale-up fermentation of 1 with A. fumigatus gave a metabolite (2) and its structure was established as bisphenol A-O-beta-D-glucopyranoside (BPAG) based on spectroscopic analyses.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Aspergillus fumigatus / drug effects
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Aspergillus fumigatus / metabolism*
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Benzhydryl Compounds
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Cell Culture Techniques
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Environmental Pollutants / adverse effects
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Environmental Pollutants / metabolism*
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Estrogens / chemistry
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Estrogens / metabolism
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Estrogens / pharmacology
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Glucosides / biosynthesis
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Glucosides / chemistry
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Phenols / chemistry
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Phenols / metabolism*
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Phenols / pharmacology
Substances
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4,4'-isopropylidenediphenol-O-glucopyranoside
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Benzhydryl Compounds
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Environmental Pollutants
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Estrogens
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Glucosides
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Phenols
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bisphenol A