Effect of testosterone therapy on QT dispersion in men with heart failure

Am J Cardiol. 2003 Nov 15;92(10):1241-3. doi: 10.1016/j.amjcard.2003.07.044.


The effects of testosterone on cardiac electrophysiology are poorly described. In this study we report the effect of physiologic testosterone therapy in 2 cohorts of men, the first with stable coronary disease and the second with congestive heart failure. Testosterone reduced QT dispersion in the heart failure cohort; no other effects were observed.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Cutaneous
  • Aged
  • Androgens / pharmacology*
  • Cohort Studies
  • Coronary Disease / physiopathology*
  • Double-Blind Method
  • Electrocardiography / drug effects*
  • Heart Failure / physiopathology*
  • Hormone Replacement Therapy*
  • Humans
  • Injections, Intramuscular
  • Male
  • Middle Aged
  • Testosterone / pharmacology*


  • Androgens
  • Testosterone