The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer

Br J Cancer. 2003 Nov 17;89(10):1906-8. doi: 10.1038/sj.bjc.6601400.


The present study examined the relationship between tumour stage, grade, T-lymphocyte subset infiltration and survival in patients who had undergone potentially curative surgery for renal clear-cell cancer (n=73). Intratumoural CD4+ T-lymphocyte infiltrate was associated with poor cancer-specific survival, independent of grade, in this cohort.

MeSH terms

  • Aged
  • Carcinoma, Renal Cell / immunology*
  • Carcinoma, Renal Cell / pathology*
  • Carcinoma, Renal Cell / surgery
  • Cohort Studies
  • Female
  • Humans
  • Immunohistochemistry
  • Kidney Neoplasms / immunology*
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / surgery
  • Male
  • Middle Aged
  • Neoplasm Staging*
  • Survival Analysis
  • T-Lymphocytes / immunology*
  • Treatment Outcome