Genome stability: a new member of the RFC family

Jiyoung Kim; Stuart A MacNeill

doi:10.1016/j.cub.2003.10.048

Genome stability: a new member of the RFC family

Curr Biol. 2003 Nov 11;13(22):R873-5. doi: 10.1016/j.cub.2003.10.048.

Authors

Jiyoung Kim¹, Stuart A MacNeill

Affiliation

¹ Wellcome Trust Centre for Cell Biology, University of Edinburgh, King's Buildings, Edinburgh EH9 3JR, Scotland, UK.

PMID: 14614842
DOI: 10.1016/j.cub.2003.10.048

Abstract

Three distinct forms of replication factor C are known to play vital roles in genome replication and integrity in eukaryotic cells. A fourth such complex has recently been identified; initial results suggest that this new family member plays an important role during S phase.

Publication types

Review

MeSH terms

DNA / metabolism
DNA Replication / genetics
DNA-Binding Proteins / genetics*
DNA-Binding Proteins / metabolism*
Genomic Instability / genetics*
Proliferating Cell Nuclear Antigen / metabolism
Replication Protein C
S Phase / genetics

Substances

DNA-Binding Proteins
Proliferating Cell Nuclear Antigen
DNA
Replication Protein C