Priming the hematopoietic pump

Immunity. 2003 Nov;19(5):633-4. doi: 10.1016/s1074-7613(03)00302-9.


Markers of multiple hematopoietic lineages are expressed in multipotent progenitors, a phenomenon referred to as "lineage priming." A new study in this issue of Immunity provides compelling evidence that such "promiscuous" gene expression occurs in hematopoietic stem cells and does not interfere with their long-term repopulation potential.

Publication types

  • Comment

MeSH terms

  • Cell Differentiation / immunology
  • Cell Differentiation / physiology*
  • Gene Expression Regulation
  • Hematopoietic Stem Cells / immunology
  • Hematopoietic Stem Cells / physiology*
  • Humans
  • Muramidase / metabolism


  • Muramidase