Comment on "Chromosomal instability and tumors promoted by DNA hypomethylation" and "Induction of tumors in nice by genomic hypomethylation"

Science. 2003 Nov 14;302(5648):1153; author reply 1153. doi: 10.1126/science.302.5648.1153a.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Azacitidine / adverse effects
  • Azacitidine / analogs & derivatives*
  • Azacitidine / therapeutic use
  • Chromosomal Instability*
  • DNA (Cytosine-5-)-Methyltransferase 1
  • DNA (Cytosine-5-)-Methyltransferases / antagonists & inhibitors
  • DNA (Cytosine-5-)-Methyltransferases / metabolism
  • DNA Methylation*
  • Decitabine
  • Genes, APC
  • Humans
  • Incidence
  • Intestinal Neoplasms / epidemiology
  • Intestinal Neoplasms / prevention & control
  • Mice
  • Neoplasms / etiology
  • Neoplasms / genetics*
  • Neoplasms / prevention & control
  • Point Mutation
  • Time Factors

Substances

  • Decitabine
  • DNA (Cytosine-5-)-Methyltransferase 1
  • DNA (Cytosine-5-)-Methyltransferases
  • Azacitidine