Conventional and diffusion-weighted MRI in the evaluation of methanol poisoning

Acta Radiol. 2003 Nov;44(6):691-5. doi: 10.1046/j.1600-0455.2003.00138.x.


Cerebral lesions were studied in 2 methanol-poisoned patients using conventional magnetic resonance imaging (MRI). In 1 patient, diffusion-weighted MRI (DWI) was also performed. In this patient, conventional MRI showed symmetrical, bilateral increased signal in the lentiform nuclei, involving predominantly putamina, but also extending into the corona radiata, centrum semiovale and subcortical white matter. DWI showed decreased diffusion, which most probably reflects cytotoxic edema. In the other patient, fluid attenuated-inversion recovery (FLAIR) and T2-weighted images showed hyperintensity in the putamina, characteristic of post-necrotic changes.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology*
  • Diffusion Magnetic Resonance Imaging
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Methanol / poisoning*
  • Middle Aged


  • Methanol