Giant keratoacanthoma arising in hypertrophic lichen planus

Australas J Dermatol. 2003 Nov;44(4):267-9. doi: 10.1046/j.1440-0960.2003.00006.x.


A 45-year-old man presented with a rapidly enlarging tumour in an area of long-standing hypertrophic lichen planus of the lower leg. Histological examination of the resected specimen showed it to be a giant keratoacanthoma measuring 37 x 57 mm. Neoplastic change is a rarely reported complication of chronic variants of cutaneous lichen planus. To date there have been only two reports of keratoacanthoma development in association with lichen planus.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / surgery
  • Cell Transformation, Neoplastic / pathology*
  • Follow-Up Studies
  • Humans
  • Hypertrophy / pathology
  • Immunohistochemistry
  • Keratoacanthoma / pathology*
  • Lichen Planus / pathology*
  • Male
  • Middle Aged
  • Risk Assessment
  • Severity of Illness Index
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Treatment Outcome