The use of OKT3 in steroid-resistant rejections following cadaveric kidney transplantation

Transpl Int. 1992;5 Suppl 1:S112-3. doi: 10.1007/978-3-642-77423-2_36.

Abstract

OKT3 has been proved to be effective in the treatment of steroid-resistant rejection after renal allograft transplantation. We investigated the clinical course of OKT3 recipients to find out in which cases of steroid resistance OKT3 therapy might be ineffective.

MeSH terms

  • Adult
  • Animals
  • Cadaver
  • Female
  • Graft Rejection / prevention & control*
  • Histocompatibility Testing
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Kidney Transplantation / immunology*
  • Kidney Transplantation / mortality
  • Kidney Transplantation / pathology
  • Male
  • Muromonab-CD3 / therapeutic use*
  • Steroids / adverse effects*
  • Survival Analysis
  • Time Factors
  • Tissue Donors

Substances

  • Immunosuppressive Agents
  • Muromonab-CD3
  • Steroids